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Alternate Names: Diquafosolum, Dicuafosol
CAS No: 59985-21-6
PubChem CID: 148197
Mol Formula: C18H26N4O23P4
Mol Weight: 790.3 g/mol
IUPAC Name: [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihyd -Show More
Commercial / Development Status: Commercial
Source / Manufacturing Origin: Synthetic
API Description: Diquafosol is a synthetic purinergic P2Y₂ receptor agonist used as an Active Pharmaceutical Ingredient (API) in ophthalmic preparations for the treatment of dry eye disease.Diquafosol acts by stimulating P2Y₂ receptors on the ocular surface and conjunctival epithelial cells. This stimulation enhances aqueous tear secretion and mucin production, improving tear film stability and ocular surface hydration.
