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Alternate Names: 1,3,2-Dioxaborolane-4-acetic acid, 2-[(1R)-1-[[2-[[[(2S)-1-(2,4-difluorophenyl)-2-azetidinyl]carbonyl]amino]acetyl]amino]-3-methylbutyl]-5-oxo-, (4S)-, Velcade
CAS No: 2409841-51-4
PubChem CID: 147112102
Mol Formula: C21H26BF2N3O7
Mol Weight: 481.3 g/mol
IUPAC Name: 2-[(4S)-2-[(1R)-1-[[2-[[(2S)-1-(2,4-difluorophenyl)azetidine-2-carbonyl]amino]acetyl]amino]-3-methylbutyl]-5-oxo-1,3,2-dioxaborolan-4-yl]acetic acid
Commercial / Development Status: Clinical APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Davelizomib is a small-molecule, reversible proteasome inhibitor designed to target the chymotrypsin-like activity of the 20S proteasome. By interfering with protein degradation pathways, it affects cellular processes such as cell cycle regulation and apoptosis. Davelizomib has been investigated primarily in the context of anticancer research as a potential therapeutic agent.
