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Alternate Names: Daprodustatum, GSK-1278863
CAS No: 960539-70-2
Mol Formula: C19H27N3O6
Mol Weight: 393.4 g/mol
IUPAC Name: 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinane-5-carbonyl)amino]acetic acid
API Description: Daprodustat is a member of the class of barbiturates that is barbituric acid substituted by cyclohexyl groups at positions 1 and 3, and by a (carboxymethyl)aminocarbonyl group at position 5. It is an inhibitor of hypoxia-inducible factor prolyl hydroxylase developed by GlaxoSmithKline for the treatment of anaemia in patients with chronic kidney disease. It has a role as an anti-anaemic agent, an EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor and an antiviral agent. It is a member of barbiturates, a secondary carboxamide, a N-acylglycine and an oxo monocarboxylic acid.
