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Alternate Names: Excenel, Ceftiofurum, Naxcel (veterinary)
CAS No: 80370-57-6
Mol Formula: C19H17N5O7S3
Mol Weight: 523.56 g/mol
IUPAC Name: (6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino}-3-[(furan-2-carbonyl)sulfanyl]methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-e -Show More
API Description: Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. It is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported. The metabolite desfurolyceftiofur also has antibiotic activity, consequently the two compounds are measured together to monitor for antibiotic activity in the milk.
