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Alternate Names: Velactis, Caberlin, Dostinex
CAS No: 81409-90-7
PubChem CID: 54746
Mol Formula: C26H37N5O2
Mol Weight: 451.6 g/mol
IUPAC Name: (6aR,9R,10aR)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
Therapeutic use: Antiparkinsonian Agents
Drug Class: Dopamine agents, Fertility agents, Neurotransmitter agents
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Semi-synthetic APIs
API Description: Cabergoline is an N-acylurea that is (8R)-ergoline-8-carboxamide in which the hydrogen attached to the piperidine nitrogen (position 6) is substituted by an allyl group and the hydrogens attached to the carboxamide nitrogen are substituted by a 3-(dimethylamino)propyl group and an N-ethylcarbamoyl group. A dopamine D2 receptor agonist, cabergoline is used in the management of Parkinson's disease and of disorders associated with hyperprolactinaemia. It has a role as a dopamine agonist, an antiparkinson drug and an antineoplastic agent.
