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Alternate Names: Bronuck, Xibrom, Bromfenac sodium anhydrous
CAS No: 91714-93-1
PubChem CID: 23693301
Mol Formula: C15H11BrNNaO3
Mol Weight: 356.15 g/mol
IUPAC Name: sodium;2-[2-amino-3-(4-bromobenzoyl)phenyl]acetate
API Description: Bromfenac Sodium is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory activities. Upon ophthalmic administration, bromfenac binds to and inhibits the activity of cyclooxygenase II (COX II), an enzyme which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins (PG). By inhibiting PG formation, bromfenac is able to inhibit PG-induced inflammation, thereby preventing vasodilation, leukocytosis, disruption of the blood-aqueous humor barrier, an increase in vascular permeability and an increase in intraocular pressure
