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Alternate Names: Finacea, Anchoic acid, Lepargylic acid, Skinoren
CAS No: 123-99-9
PubChem CID: 2266
Mol Formula: C9H16O4
Mol Weight: 188.22 g/mol
IUPAC Name: nonanedioic acid
Therapeutic use: Acne agents, Dermatologicals
Drug Class: Keratolytics
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Natural APIs
API Description: Nonanedioic acid is an alpha,omega-dicarboxylic acid that is heptane substituted at positions 1 and 7 by carboxy groups. It has a role as an antibacterial agent, an antineoplastic agent, a dermatologic drug and a plant metabolite. It is a dicarboxylic fatty acid and an alpha,omega-dicarboxylic acid. It is a conjugate acid of an azelaate(2-) and an azelaate. Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is also produced by Malassezia furfur, also known as Pityrosporum ovale, which is a species of fungus that is normally found on human skin. Azelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.
