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Alternate Names: ICI 350, 6-amino-2-(2-chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one
CAS No: 3567-76-8
PubChem CID: 18934
Mol Formula: C10H11ClN2O2
Mol Weight: 226.66 g/mol
IUPAC Name: 6-amino-2-(2-chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one
Commercial / Development Status: Discontinued APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Aminochlorthenoxazine is an older first-generation antihistamine that was used to treat allergic conditions such as allergic rhinitis, urticaria, and general itching. Like many drugs in its class, it worked by blocking H₁ receptors to reduce the effects of histamine, while also producing mild sedation. Although it was once used for symptomatic allergy relief, it is now considered an outdated active pharmaceutical ingredient and has largely been replaced by newer antihistamines that offer better safety and fewer sedative side effects.
