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Alternate Names: Ethyol (TN), Ethanethiol, 2-[(3-aminopropyl)amino]-, dihydrogen phosphate (ester),trihydrate
CAS No: 112901-68-5
PubChem CID: 148139
Mol Formula: C5H21N2O6PS
Mol Weight: 268.27 g/mol
IUPAC Name: 2-(3-aminopropylamino)ethylsulfanylphosphonic acid;trihydrate
API Description: Amifostine Trihydrate (Ethyol) is a cytoprotective drug used in cancer therapy to shield healthy tissues from the damaging effects of chemotherapy (like cisplatin-induced kidney damage) and radiation, particularly preventing dry mouth (xerostomia) in head/neck cancer patients, by scavenging free radicals and binding to toxic metabolites, though its use is limited by side effects like low blood pressure. It's given intravenously before treatment, acting selectively on healthy cells over tumor cells.
