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Alternate Names: SB19732, NCGC00538163-01
CAS No: 841301-32-4
Mol Formula: C24H26N4O5S
Mol Weight: 482.56 g/mol
IUPAC Name: N-(2,6-dimethylphenyl)-N-[2-[4-(1,2,4-oxadiazol-3-yl)anilino]-2-oxoethyl]-1,1-dioxothiane-4-carboxamide
API Description: Amenamevir is an antiviral agent used for the treatment of herpes zoster (shingles). It functions as a helicase-primase inhibitor, disrupting viral DNA replication and thereby reducing the severity and duration of shingles outbreaks. Amenamevir is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2. Amenamenir stabilizes the interaction between the helicase-primase and its DNA substrates, preventing the progression through helicase or primase catalytic cycles, thus interfering with viral DNA replication and viral growth.