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Alternate Names: alectinibum, AF-802, Alecensa
CAS No: 1256580-46-7
PubChem CID: 49806720
Mol Formula: C30H34N4O2
Mol Weight: 482.6 g/mol
IUPAC Name: 9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
API Description: Alectinib is an oral medication used to treat non-small cell lung cancer (NSCLC) that is ALK-positive. It works by inhibiting anaplastic lymphoma kinase (ALK), thereby preventing cancer cell growth. Alectinib is an organic heterotetracyclic compound that is 6,6-dimethyl-5,6-dihydro-11H-benzo[b]carbazol-11-one carrying additional cyano, 4-(morpholin-4-yl)piperidin-1-yl and ethyl substituents at positions 3, 8 and 9 respectively. Used (as the hydrochloride salt) for the treatment of patients with anaplastic lymphoma kinase-positive, metastatic non-small cell lung cancer. It has a role as an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an antineoplastic agent. It is an organic heterotetracyclic compound, a member of morpholines, a member of piperidines, a nitrile and an aromatic ketone. It is a conjugate base of an alectinib(1+).
