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Alternate Names: AICA-riboside, Arasine, Protara, Acadra
CAS No: 2627-69-2
PubChem CID: 17513
Mol Formula: C9H14N4O5
Mol Weight: 258.23 g/mol
IUPAC Name: 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide
Commercial / Development Status: Discontinued APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Acadesine is a 1-ribosylimidazolecarboxamide in which the carboxamide group is situated at position 4 of the imidazole ring, which is further substituted at position 5 by an amino group. A purine nucleoside analogue and activator of AMP-activated protein kinase, it is is used for the treatment of acute lymphoblastic leukemia and is reported to have cardioprotective effects. It has a role as a platelet aggregation inhibitor and an antineoplastic agent. It is an aminoimidazole, a nucleoside analogue and a 1-ribosylimidazolecarboxamide.
