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Alternate Names: Panzem, 2-methoxy-17beta-estradiol, 2-Hydroxyestradiol 2-methyl ether
CAS No: 362-07-2
PubChem CID: 66414
Mol Formula: C19H26O3
Mol Weight: 302.4 g/mol
IUPAC Name: (8R,9S,13S,14S,17S)-2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
API Description: 2-Methoxyestradiol (2-ME2) is an estrogen metabolite with established use in cancer treatment and potential applications in cardiovascular health and inflammatory conditions. Its uses stem from its antiangiogenic (inhibiting blood vessel growth) and antimitotic (inhibiting cell division) properties, which target both tumor cells and their blood supply. By inducing apoptosis and cell cycle arrest, 2-ME2 inhibits tumor growth and metastasis, and it also has a role in preventing conditions like atherosclerosis.
