(R)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid (CAS No: 20445-31-2) is a key pharmaceutical intermediate used in the synthesis of APIs Simvastatin, Rosuvastatin, Fluvastatin, Pravastatin and Atorvastatin. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Moshers's acid, alpha-Methoxy-alpha-trifluoromethylphenylacetic acid, (+)-
CAS No: 20445-31-2
PubChem CID: 2723917
Mol Formula: C10H9F3O3
Mol Weight: 234.17 g/mol
Used in APIs: Simvastatin, Rosuvastatin, Fluvastatin, Pravastatin and Atorvastatin
IUPAC Name: (2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid
API Intermediate Description: (R)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid (commonly known as (R)-MTPA or (R)-Mosher’s acid) is a chiral carboxylic acid widely used in stereochemical analysis and asymmetric synthesis. It appears as a white crystalline solid, sparingly soluble in water but soluble in organic solvents such as chloroform, methanol, and ether.
