(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine (CAS No: 877399-00-3) is a key pharmaceutical intermediate used in the synthesis of APIs Crizotinib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 5-Bromo-3-((1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-pyridinamine, Crizotinib Intermediate
CAS No: 877399-00-3
PubChem CID: 11689426
Mol Formula: C13H10BrCl2FN2O
Mol Weight: 380.0 g/mol
Used in API: Crizotinib
IUPAC Name: 5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine
API Intermediate Description: (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine is a chiral heteroaromatic compound featuring a brominated pyridine core linked to a substituted fluorinated phenyl group via an ethoxy side chain. The presence of multiple halogens and a stereogenic center enhances its relevance in structure–activity relationship studies. It is typically used as an intermediate in medicinal and agrochemical research.
