N-Methyldesloratadine (CAS No: 38092-89-6) is a key pharmaceutical intermediate used in the synthesis of APIs Loratadine and Desloratadine. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 8-chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, Loratadine impurity G
CAS No: 38092-89-6
PubChem CID: 31843
Mol Formula: C20H21ClN2
Mol Weight: 324.8 g/mol
Used in APIs: Loratadine and Desloratadine
IUPAC Name: 13-chloro-2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene
API Intermediate Description: N-Methyldesloratadine is a metabolite of desloratadine, an antihistamine, in which a methyl group is attached to the nitrogen atom of the parent compound. It retains the tricyclic and piperidine-based structure characteristic of desloratadine. This compound is relevant in pharmacology for studying metabolism, pharmacokinetics, and the activity of antihistamines.
