Methyl (S)-2-(((benzyloxy)carbonyl)amino)-3-((S)-morpholin-2-yl)propanoate (CAS No: 2641824-62-4) is a key pharmaceutical intermediate used in the synthesis of APIs Zoldonrasib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Methyl (2S)-2-{[(benzyloxy)carbonyl]amino}-3-[(2S)-morpholin-2-yl]propanoate
CAS No: 2641824-62-4
PubChem CID: 156679002
Mol Formula: C16H22N2O5
Mol Weight: 322.36 g/mol
Used in API: Zoldonrasib
IUPAC Name: methyl (2S)-3-[(2S)-morpholin-2-yl]-2-(phenylmethoxycarbonylamino)propanoate
API Intermediate Description: Zoldonrasib (RMC-9805) is a selective KRAS G12D inhibitor, and methyl (S)-2-(((benzyloxy)carbonyl)amino)-3-((S)-morpholin-2-yl)propanoate is a chiral amino-acid/morpholine intermediate used in its synthesis. The compound contains a Cbz-protected amino group, methyl ester, and chiral morpholine substituent, providing the required stereochemical and functional framework for subsequent coupling reactions. Further deprotection, hydrolysis, and coupling transformations convert this intermediate into more advanced intermediates used to construct the final zoldonrasib API.
