methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate (CAS No: 676326-36-6) is a key pharmaceutical intermediate used in the synthesis of APIs Nintedanib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Nintedanib Impurity 4, 1-acetyl-6-methoxycarbonyl-2-indolinone
CAS No: 676326-36-6
PubChem CID: 44191304
Mol Formula: C12H11NO4
Mol Weight: 233.22 g/mol
Used in API: Nintedanib
IUPAC Name: methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate
API Intermediate Description: Methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate is primarily used as a crucial pharmaceutical intermediate and building block in organic synthesis, particularly for creating complex drug molecules like Nintedanib, an important drug for idiopathic pulmonary fibrosis (IPF) and certain cancers, functioning as an angiokinase and tyrosine kinase inhibitor. It also serves as a standard for identifying impurities in Nintedanib manufacturing, highlighting its role in quality control within the pharmaceutical industry.
