Ethyl (2R,3R)-3-cyclopropylaziridine-2-carboxylate (CAS No: 2864383-25-3) is a key pharmaceutical intermediate used in the synthesis of APIs Zoldonrasib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Ethyl (2R,3R)-3-cyclopropylaziridine-2-carboxylate
CAS No: 2864383-25-3
PubChem CID: 169545067
Mol Formula: C8H13NO2
Mol Weight: 155.19 g/mol
Used in API: Zoldonrasib
IUPAC Name: ethyl 3-cyclopropylaziridine-2-carboxylate
API Intermediate Description: Zoldonrasib (RMC-9805) is a selective KRAS G12D inhibitor, and ethyl (2R,3R)-3-cyclopropylaziridine-2-carboxylate is a chiral aziridine intermediate used in its synthesis. The strained aziridine ring, cyclopropyl group, and stereochemically defined ester functionality provide a versatile building block for subsequent ring-opening, coupling, and functional-group transformations. These reactions help introduce the required chiral structural elements into advanced intermediates that ultimately contribute to the zoldonrasib API.
