(5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol dihydrochloride (CAS No: 1373116-07-4) is a key pharmaceutical intermediate used in the synthesis of APIs Rimegepant. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Rimegepant Metabolite M18, Rimegepant Intermediate
CAS No: 1373116-07-4
PubChem CID: 68278585
Mol Formula: C16H18Cl2F2N2O
Mol Weight: 363.2 g/mol
Used in API: Rimegepant
IUPAC Name: (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol;dihydrochloride
API Intermediate Description: (5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol dihydrochloride is a chiral, nitrogen-containing heterocyclic compound featuring a cycloheptapyridine core with an amino group at C‑5, a hydroxyl at C‑9, and a difluorophenyl substituent at C‑6. The defined (5S,6S,9R) stereochemistry and dihydrochloride salt enhance its stability, solubility, and three-dimensional conformation. This compound is commonly used as a synthetic intermediate or bioactive scaffold in medicinal chemistry research.
![(5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-ol dihydrochloride](https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=68278585&t=l)
