5-Methylisoxazole-4-carboxylic acid (CAS No: 42831-50-5) is a key pharmaceutical intermediate used in the synthesis of APIs Leflunomide. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Leflunomide impurity D [EP], 4-Isoxazolecarboxylic acid, 5-methyl-
CAS No: 42831-50-5
PubChem CID: 1425240
Mol Formula: C5H5NO3
Mol Weight: 127.10 g/mol
Used in API: Leflunomide
IUPAC Name: 5-methyl-1,2-oxazole-4-carboxylic acid
API Intermediate Description: 5-Methylisoxazole-4-carboxylic acid is a key starting intermediate used in the synthesis of Leflunomide, an immunomodulatory drug for rheumatoid arthritis. This intermediate provides the essential isoxazole ring system that forms a core structural component of Leflunomide. During the synthesis, it undergoes conversion into the corresponding amide and is further transformed through cyclization and functional-group modifications to build the final active molecule. Its defined heterocyclic framework and reactivity make it crucial for ensuring an efficient, reliable, and high-purity synthetic route to Leflunomide.
