(5-Bromo-2-chlorophenyl)(4-fluorophenyl)methanone (CAS No: 915095-85-1) is a key pharmaceutical intermediate used in the synthesis of APIs Empagliflozin. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: (5-bromo-2-chloro-phenyl)-(4-fluorophenyl)methanone, Methanone, (5-bromo-2-chlorophenyl)(4-fluorophenyl)-
CAS No: 915095-85-1
PubChem CID: 15941367
Mol Formula: C13H7BrClFO
Mol Weight: 313.55 g/mol
Used in API: Empagliflozin
IUPAC Name: (5-bromo-2-chlorophenyl)-(4-fluorophenyl)methanone
API Intermediate Description: (5-Bromo-2-chlorophenyl)(4-fluorophenyl)methanone is a key advanced intermediate used in the manufacturing process of Empagliflozin, a sodium–glucose cotransporter-2 (SGLT2) inhibitor for type-2 diabetes. This intermediate provides a crucial aryl–aryl ketone framework that is later transformed into the substituted tetrahydrofuran-based core characteristic of Empagliflozin. Its predefined substitution pattern helps ensure the correct stereochemical and structural arrangement required in the final API. Because of its stability and suitability for downstream transformations, this compound enables a more efficient, consistent, and high-purity synthetic route for producing Empagliflozin.
