(4R,5R)-3,3-difluoro-5-(hydroxymethyl)oxolane-2,4-diol (CAS No: 861445-88-7) is a key pharmaceutical intermediate used in the synthesis of APIs Gemcitabine. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 2-deoxy-2,2-difluoro-d-ribofuranose, Gemcitabine Intermediate
CAS No: 861445-88-7
PubChem CID: 14057748
Mol Formula: C5H8F2O4
Mol Weight: 170.11 g/mol
Used in API: Gemcitabine
IUPAC Name: (4R,5R)-3,3-difluoro-5-(hydroxymethyl)oxolane-2,4-diol
API Intermediate Description: (4R,5R)-3,3-difluoro-5-(hydroxymethyl)oxolane-2,4-diol is a fluorinated furanose analog featuring a difluoromethylene group at the 3-position. It serves as a key intermediate in the synthesis of modified nucleosides and carbohydrate-based therapeutics. The presence of fluorine atoms enhances chemical stability and can significantly influence biological activity.