4-(Methylsulfonyl)aniline hydrochloride (CAS No: 177662-76-9) is a key pharmaceutical intermediate used in the synthesis of APIs Esaxerenone. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 4-methylsulfonylaniline Hydrochloride, Benzenamine, 4-(methylsulfonyl)-, hydrochloride (1:1)
CAS No: 177662-76-9
PubChem CID: 2735180
Mol Formula: C7H10ClNO2S
Mol Weight: 207.68 g/mol
Used in API: Esaxerenone
IUPAC Name: 4-methylsulfonylaniline;hydrochloride
API Intermediate Description: 4-(Methylsulfonyl)aniline hydrochloride (MSAH) is primarily used as a crucial pharmaceutical intermediate for synthesizing new drugs, especially non-steroidal anti-inflammatory drugs (NSAIDs) and potential COX-2 selective inhibitors, by incorporating its sulfonyl aniline structure into molecules like naproxen or diclofenac to enhance anti-inflammatory properties and selectivity. It acts as a key building block in medicinal chemistry, not for direct consumer use, and requires careful handling due to its irritant and potentially harmful nature.