4-Chloro-N-methylpicolinamide (CAS No: 220000-87-3) is a key pharmaceutical intermediate used in the synthesis of APIs Sorafenib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: N-METHYL 4-CHLOROPICOLINAMIDE,2-Pyridinecarboxamide, 4-chloro-N-methyl-
CAS No: 220000-87-3
PubChem CID: 1476814
Mol Formula: C7H7ClN2O
Mol Weight: 170.59 g/mol
Used in API: Sorafenib
IUPAC Name: 4-chloro-N-methylpyridine-2-carboxamide
API Intermediate Description: 4-Chloro-N-methylpicolinamide is a halogenated pyridine amide used as a synthetic intermediate in pharmaceutical and agrochemical chemistry. It consists of a picolinamide (2-pyridinecarboxamide) core with a chloro substituent at the 4-position and a N-methylated amide nitrogen. The pyridine ring provides basic heteroaromatic character, while the amide functionality offers predictable hydrogen-bonding and stability. The aryl chloride can serve as a handle for further functionalization under appropriate conditions.
