4-Chloro-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester (CAS No: 5909-24-0) is a key pharmaceutical intermediate used in the synthesis of APIs Avanafil. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 4-chloro-5-ethoxycarbonyl-2-methylthiopyrimidine,ethyl 4-chloro-2-(methylthio)pyrimidine -5-carboxylate
CAS No: 5909-24-0
PubChem CID: 80008
Mol Formula: C8H9ClN2O2S
Mol Weight: 232.69 g/mol
Used in API: Avanafil
IUPAC Name: ethyl 4-chloro-2-methylsulfanylpyrimidine-5-carboxylate
API Intermediate Description: 4-Chloro-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester is a halogenated pyrimidine derivative used strictly as a synthetic intermediate in pharmaceutical and agrochemical chemistry.The molecule features a pyrimidine heterocyclic core substituted with a chloro group at the 4-position, a methylthio (–SCH₃) group at the 2-position, and an ethyl ester at the 5-carboxylate position. This combination of functional groups gives the compound high synthetic flexibility.
