4-Bromopyrazole (CAS No: 2075-45-8) is a key pharmaceutical intermediate used in the synthesis of APIs Ruxolitinib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 4-Bromo-1H-pyrazole, 1H-Pyrazole, 4-bromo-
CAS No: 2075-45-8
PubChem CID: 16375
Mol Formula: C3H3BrN2
Mol Weight: 146.97 g/mol
Used in API: Ruxolitinib
IUPAC Name: 4-bromo-1H-pyrazole
API Intermediate Description: 4-Bromopyrazole is a key building block used in the synthesis of Ruxolitinib, a JAK1/2 inhibitor, serving as the raw material to introduce the functionalized pyrazole ring. It is primarily employed in coupling reactions to form the core intermediate, (R)-3-(4-bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile.
