4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide (CAS No: 757251-39-1) is a key pharmaceutical intermediate used in the synthesis of APIs Regorafenib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide, Regorafenib EP Impurity A
CAS No: 757251-39-1
PubChem CID: 46835219
Mol Formula: C13H12FN3O2
Mol Weight: 261.25 g/mol
Used in API: Regorafenib
IUPAC Name: 4-(4-amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
API Intermediate Description: 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is primarily used as a crucial synthetic intermediate for manufacturing the anticancer drug Regorafenib (Stivarga), a multikinase inhibitor used for advanced colorectal cancer and other cancers, serving as a building block in its complex synthesis process, often appearing as an impurity or reference material in Regorafenib production.