(3aR,4R,6R,6aR)-4-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-6-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-4-carbonitrile (CAS No: 1191237-80-5) is a key pharmaceutical intermediate used in the synthesis of APIs Remdesivir. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Remdesivir O-desphosphate acetonide impurity, D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-3,4-O-(1-methylethylidene)-
CAS No: 1191237-80-5
PubChem CID: 58527338
Mol Formula: C15H17N5O4
Mol Weight: 331.33 g/mol
Used in API: Remdesivir
IUPAC Name: (3aR,4R,6R,6aR)-4-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-6-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-4-carbonitrile
API Intermediate Description: A stereochemically defined fused heterocyclic compound featuring a substituted furo[3,4-d][1,3]dioxole core with multiple chiral centers, bearing a 4-aminopyrrolo[2,1-f][1,2,4]triazinyl moiety along with hydroxymethyl and carbonitrile functional groups, and combining a rigid bicyclic architecture with polar substituents that suggest potential relevance in medicinal or antiviral research.
![(3aR,4R,6R,6aR)-4-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-6-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-4-carbonitrile](https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=58527338&t=l)
