3-Nitro-4-(((tetrahydro-2H-pyran-4-yl) methyl)amino) benzene sulfonamide (CAS No: 1228779-96-1) is a key pharmaceutical intermediate used in the synthesis of APIs Venetoclax. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 3-nitro-4-(oxan-4-ylmethylamino)benzenesulfonamide, Benzenesulfonamide, 3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]-
CAS No: 1228779-96-1
PubChem CID: 57474953
Mol Formula: C12H17N3O5S
Mol Weight: 315.35 g/mol
Used in API: Venetoclax
IUPAC Name: 3-nitro-4-(oxan-4-ylmethylamino)benzenesulfonamide
API Intermediate Description: 3-Nitro-4-(((tetrahydro-2H-pyran-4-yl) methyl)amino) benzene sulfonamide is a pharmaceutical intermediate used in the synthesis of several targeted cancer drugs. Its primary use is as a building block for Venetoclax, a medication used to treat certain types of chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). It is also used to create other inhibitors, such as those for BTK, PI3K, and JAK-2 pathways.