3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo(d)oxazol-2(3H)-one (CAS No: 1220696-32-1) is a key pharmaceutical intermediate used in the synthesis of APIs Brensocatib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 3-Methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-ylboronic acid pinacol ester, 2(3H)-Benzoxazolone, 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CAS No: 1220696-32-1
PubChem CID: 59535069
Mol Formula: C14H18BNO4
Mol Weight: 275.11 g/mol
Used in API: Brensocatib
IUPAC Name: 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazol-2-one
API Intermediate Description: 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one is a boronic ester–functionalized benzoxazolone derivative. It is commonly used as a synthetic intermediate, particularly in Suzuki–Miyaura cross-coupling reactions for building complex aromatic compounds.