3-Methyl-1-(2-piperidinophenyl)-1-butylamine, (S)- (CAS No: 147769-93-5) is a key pharmaceutical intermediate used in the synthesis of APIs Repaglinide. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Repaglinide specified impurity C [EP], (1S)-3-Methyl-1-(2-(piperidin-1-yl)phenyl)butan-1-amine
CAS No: 147769-93-5
PubChem CID: 10514609
Mol Formula: C16H26N2
Mol Weight: 246.39 g/mol
Used in API: Repaglinide
IUPAC Name: (1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butan-1-amine
API Intermediate Description: (S)-3-Methyl-1-(2-piperidinophenyl)-1-butylamine is the crucial chiral amine intermediate used in the synthesis of the antidiabetic drug Repaglinide. It reacts with 3-ethoxy-4-ethoxycarbonylphenylacetic acid via amide coupling to form the core structure of Repaglinide, typically involving catalysts like N,N′-dicyclohexylcarbodiimide (DCC) or N,N′-carbonyldiimidazole (CDI).
