[3-(Hydroxymethyl)phenyl]boronic acid (CAS No: 87199-15-3) is a key pharmaceutical intermediate used in the synthesis of APIs Pacritinib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 3-(Hydroxymethyl)benzeneboronic Acid, Tepotinib impurity 26
CAS No: 87199-15-3
PubChem CID: 2734662
Mol Formula: C7H9BO3
Mol Weight: 151.96 g/mol
Used in API: Pacritinib
IUPAC Name: [3-(hydroxymethyl)phenyl]boronic acid
API Intermediate Description: [3-(Hydroxymethyl)phenyl]boronic acid is a key building block in synthesizing Pacritinib, primarily used in a Suzuki-Miyaura coupling reaction with a pyrimidine derivative (like 2,4-dichloropyrimidine) to form a crucial intermediate, establishing the phenyl-pyrimidine core of the drug. This coupling connects the hydroxymethyl-substituted phenyl ring to the pyrimidine, setting up the structure for subsequent etherification and other reactions needed to complete the Pacritinib molecule.
![[3-(Hydroxymethyl)phenyl]boronic acid](https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=2734662&t=l)
