3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzoic Acid (CAS No: 162401-62-9) is a key pharmaceutical intermediate used in the synthesis of APIs Roflumilast. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Benzoic acid, 3-(cyclopropylmethoxy)-4-(difluoromethoxy)-, Roflumilast intermediate B
CAS No: 162401-62-9
PubChem CID: 2394006
Mol Formula: C12H12F2O4
Mol Weight: 258.22 g/mol
Used in API: Roflumilast
IUPAC Name: 3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid
API Intermediate Description: 3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzoic Acid (DGM) is primarily used as a crucial building block (intermediate) in synthesizing Roflumilast, a medicine for severe COPD, but research also shows it might be a potential treatment for pulmonary fibrosis by inhibiting EMT (Epithelial-Mesenchymal Transition). It acts as a precursor for Roflumilast, a PDE4 inhibitor, and shows promise in lab studies for fibrosis by targeting TGF-β1 pathways.
