3-bromo-5-iodo-2-[(1S)-1-methoxyethyl]pyridine (CAS No: 2641451-76-3) is a key pharmaceutical intermediate used in the synthesis of APIs Daraxonrasib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: (S)-3-Bromo-5-iodo-2-(1-methoxyethyl)pyridine
CAS No: 2641451-76-3
PubChem CID: 156312188
Mol Formula: C8H9BrINO
Mol Weight: 341.97 g/mol
Used in API: Daraxonrasib
IUPAC Name: 3-bromo-5-iodo-2-[(1S)-1-methoxyethyl]pyridine
API Intermediate Description: Daraxonrasib (RMC-6236) is a RAS inhibitor, and 3-bromo-5-iodo-2-[(1S)-1-methoxyethyl]pyridine is a halogenated chiral pyridine intermediate used in the synthesis of advanced intermediates for daraxonrasib. Its bromo and iodo substituents provide versatile sites for selective cross-coupling reactions, while the chiral 1-methoxyethyl group contributes to the required stereochemical architecture. Subsequent coupling and functional-group transformations of this intermediate help construct the substituted heteroaromatic portion of the daraxonrasib molecule.
![3-bromo-5-iodo-2-[(1S)-1-methoxyethyl]pyridine](https://apicule.com/wp-content/uploads/apis/c2030861b0df145daae7df7331e73945.png)
