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(2’R)-2′-Deoxy-2′-fluoro-2′-methyluridine (CAS No: 863329-66-2) API Intermediate Manufacturers

(2’R)-2′-Deoxy-2′-fluoro-2′-methyluridine (CAS No: 863329-66-2) is a key pharmaceutical intermediate used in the synthesis of APIs Ledipasvir. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.

(2’R)-2′-Deoxy-2′-fluoro-2′-methyluridine

Alternate Names: Sofosbuvir Impurity 79, Sofosbuvir Metabolites GS331007

CAS No: 863329-66-2

PubChem CID: 11311503

Mol Formula: C10H13FN2O5

Mol Weight: 260.22 g/mol

Used in API: Ledipasvir

IUPAC Name: 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione

API Intermediate Description: (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine (PSI-6206) is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine and acts as the active form (triphosphate) that inhibits hepatitis C virus (HCV) RNA polymerase, thus blocking viral RNA synthesis.

                   
(2’R)-2′-Deoxy-2′-fluoro-2′-methyluridine

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