2,3-Dichloro-6-nitrobenzonitrile (CAS No: 2112-22-3) is a key pharmaceutical intermediate used in the synthesis of APIs Anagrelide. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 5,6-dichloro-2-nitrobenzonitrile, Anagrelide Impurity 18
CAS No: 2112-22-3
PubChem CID: 2736020
Mol Formula: C7H2Cl2N2O2
Mol Weight: 217.01 g/mol
Used in API: Anagrelide
IUPAC Name: 2,3-dichloro-6-nitrobenzonitrile
API Intermediate Description: 2,3-Dichloro-6-nitrobenzonitrile is an important aromatic intermediate used in the multistep synthesis of Anagrelide. In the synthetic route, this compound provides the substituted benzene core needed to build the quinazolinone structure of Anagrelide. The nitro group is typically reduced to an amine, which then undergoes cyclization and further functional transformations to form the quinazolinone ring system. The chloro substituents help guide substitution reactions and improve the efficiency of constructing the final drug molecule, making this compound a key starting material in Anagrelide production.
