2-Methyl-5-Nitroaniline (CAS No: 99-55-8) is a key pharmaceutical intermediate used in the synthesis of APIs Enzalutamide. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 2-Methyl-5-nitrobenzenamine, 5-Nitro-2-toluidine
CAS No: 99-55-8
PubChem CID: 7444
Mol Formula: C7H8N2O2
Mol Weight: 152.15 g/mol
Used in API: Enzalutamide
IUPAC Name: 2-methyl-5-nitroaniline
API Intermediate Description: 2-Methyl-5-nitroaniline is a key aromatic intermediate used in the multistep synthesis of Enzalutamide. In the synthetic route, the nitro group is typically reduced to form the corresponding phenylenediamine derivative, which then undergoes further functionalization such as acylation, urea formation, or coupling reactions to build the core diaryl thiohydantoin structure characteristic of the final molecule. The methyl substituent contributes to the correct substitution pattern required for biological activity in the finished API.
