2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide (CAS No: 1211443-61-6) is a key pharmaceutical intermediate used in the synthesis of APIs Ribociclib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 7H-Pyrrolo[2,3-d]pyriMidine-6-carboxaMide, 2-chloro-7-cyclopentyl-N,N-diMethyl-;, Ribociclib chloro amide impurity
CAS No: 1211443-61-6
PubChem CID: 58315432
Mol Formula: C14H17ClN4O
Mol Weight: 292.76 g/mol
Used in API: Ribociclib
IUPAC Name: 2-chloro-7-cyclopentyl-N,N-dimethylpyrrolo[2,3-d]pyrimidine-6-carboxamide
API Intermediate Description: 2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[3-d]pyrimidine-6-carboxamide is a critical, advanced intermediate used in the synthesis of the CDK4/6 inhibitor drug Ribociclib. It acts as a key building block in the pyrrolo[3-d]pyrimidine core construction, typically coupled with 5-piperazin-1-yl-pyridin-2-ylamine to form the final active pharmaceutical ingredient (API).
![2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide](https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=58315432&t=l)
