(1S)-1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine (CAS No: 608141-42-0) is a key pharmaceutical intermediate used in the synthesis of APIs Apremilast. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: (1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine, Apremilast Impurity 79
CAS No: 608141-42-0
PubChem CID: 11282264
Mol Formula: C12H19NO4S
Mol Weight: 273.35 g/mol
Used in API: Apremilast
IUPAC Name: (1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine
API Intermediate Description: The compound (1S)-1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine is a crucial intermediate in the synthesis of Apremilast, a phosphodiesterase 4 (PDE4) inhibitor used to treat conditions like psoriatic arthritis and plaque psoriasis, working by modulating inflammatory responses. This specific chiral amine intermediate, often used as its N-acetyl-L-leucine salt, is a key building block to form the final active pharmaceutical ingredient (API).
