(1R,5S)-6,6-Dimethyl-3-oxabicyclo(3.1.0)hexane-2,4-dione (CAS No: 67911-21-1) is a key pharmaceutical intermediate used in the synthesis of APIs Boceprevir. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 6,6-Dimethyl-3-oxabicyclo(3.1.0)hexane-2,4-dione, Caronic anhydride
CAS No: 67911-21-1
PubChem CID: 10374536
Mol Formula: C7H8O3
Mol Weight: 140.14 g/mol
Used in API: Boceprevir
IUPAC Name: 6,6-dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione
API Intermediate Description: (1R,5S)-6,6-Dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione—also known as Caronic anhydride—is primarily used as a chemical intermediate in organic synthesis, rather than as a therapeutic agent. It serves as a versatile building block for constructing more complex molecules due to its strained bicyclic structure and reactive dione functionality. The compound is employed in research chemistry, including studies involving Meldrum’s acid derivatives and cyclopropane synthesis, and it also appears in the manufacturing pathways of certain pharmaceutical intermediates, although it is not itself an active drug. Commercial suppliers classify it strictly for research and development use, noting that it is moisture sensitive and may cause irritation upon contact or inhalation, so it requires proper laboratory handling.
