(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (CAS No: 220352-38-5) is a key pharmaceutical intermediate used in the synthesis of APIs Ticagrelor. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Ticagrelor Impurity E, Cyclopropanamine, 2-(3,4-difluorophenyl)-, (1R,2S)-
CAS No: 220352-38-5
PubChem CID: 9834068
Mol Formula: C9H9F2N
Mol Weight: 169.17 g/mol
Used in API: Ticagrelor
IUPAC Name: trans-(1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine
API Intermediate Description: (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is a chiral cyclopropane derivative widely used as a key intermediate in the synthesis of central nervous system (CNS) active pharmaceutical ingredients. The strained cyclopropane ring provides conformational rigidity, while the 3,4-difluorophenyl group enhances lipophilicity and metabolic stability.