1,2-Ethanediamine, N1,N1,N2-trimethyl- (CAS No: 142-25-6) is a key pharmaceutical intermediate used in the synthesis of APIs Alflutinib, Aumolertinib, Mobocertinib, Osimertinib, Asandeutertinib, Brigatinib, Lazertinib and Sunvozertinib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: N,N,N'-Trimethylethylenediamine, Dimethyl(2-(methylamino)ethyl)amine
CAS No: 142-25-6
PubChem CID: 67338
Mol Formula: C5H14N2
Mol Weight: 102.18 g/mol
Used in APIs: Alflutinib, Aumolertinib, Mobocertinib, Osimertinib, Asandeutertinib, Brigatinib, Lazertinib and Sunvozertinib
IUPAC Name: N,N',N'-trimethylethane-1,2-diamine
API Intermediate Description: 1,2-Ethanediamine, N1,N1,N2-trimethyl-, also known as N,N,N′-trimethylethylenediamine (TMEDA), is used as a ligand in coordination chemistry, a catalyst in organic synthesis (particularly for reactions involving nucleophilic substitutions), and to stabilize reactive intermediates. It is a colorless to pale yellow liquid with a strong odor.