1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine (CAS No: 253168-94-4) is a key pharmaceutical intermediate used in the synthesis of APIs Apremilast. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulfonyl)eth-2-ylamine, 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine
CAS No: 253168-94-4
PubChem CID: 11288792
Mol Formula: C12H19NO4S
Mol Weight: 273.35 g/mol
Used in API: Apremilast
IUPAC Name: 1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine
API Intermediate Description: The compound 1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine (specifically its (S)-enantiomer) is a key intermediate in the synthesis of Apremilast, a phosphodiesterase 4 (PDE4) inhibitor used to treat inflammatory conditions like psoriatic arthritis and plaque psoriasis. This specific amine is crucial for forming the core structure of Apremilast, also known as Otezla.
