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Alternate Names: Eftilagimod alpha, Efti
CAS No: 928150-91-8
PubChem CID: 72941955
Mol Formula: C56H78N18O14S
Mol Weight: 1259.4 g/mol
IUPAC Name: (4R)-4-[[(2R)-6-amino-2-[[(2R)-2-[[4-(aminocarbamothioylamino)benzoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]hexanoyl]amino]-5-[[(2R)-1-amino-6-[bi -Show More
Commercial / Development Status: Clinical APIs
Source / Manufacturing Origin: Peptide APIs
API Description: IMP321, also known as eftilagimod alpha, is a soluble LAG-3Ig fusion protein that acts as an antigen presenting cell (APC) activator. It's being developed to enhance the immune response against tumors by stimulating dendritic cells (DCs) through MHC class II molecules. This leads to the activation of CD8+ T cells, which are crucial for fighting cancer. IMP321 is being investigated for its potential in various cancers, including metastatic breast cancer, non-small cell lung cancer, and head and neck squamous cell carcinoma.
