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Alternate Names: Idamycin, Idamycin PFS, 4-Demethoxydaunorubicin hydrochloride
CAS No: 57852-57-0
PubChem CID: 636362
Mol Formula: C26H28ClNO9
Mol Weight: 534.0 g/mol
IUPAC Name: (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride
Therapeutic use: Antineoplastics
Drug Class: Anthracyclines, Antineoplastic agents, Cytotoxics
Commercial / Development Status: Commercial
Source / Manufacturing Origin: Semi-synthetic
API Description: Idarubicin Hydrochloride is the hydrochloride salt of the anthracycline antineoplastic antibiotic idarubicin. Idarubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds
