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Alternate Names: LH-RH hydrochloride, Factrel
CAS No: 51952-41-1
PubChem CID: 23624131
Mol Formula: C55H76ClN17O13
Mol Weight: 1218.7 g/mol
IUPAC Name: (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1- -Show More
API Description: Gonadorelin hydrochloride is a synthetic form of gonadotropin-releasing hormone (GnRH) used primarily in the diagnosis and treatment of reproductive and hormonal disorders. It acts by stimulating the anterior pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are essential for normal reproductive function. Clinically, it is commonly administered via the parenteral route—either intravenously or subcutaneously—as it is not effective when taken orally due to rapid degradation in the gastrointestinal tract. Gonadorelin hydrochloride is used in the evaluation of pituitary function, particularly in patients with delayed puberty, amenorrhea, or suspected hypogonadotropic hypogonadism. It is also used as a diagnostic tool to differentiate between hypothalamic and pituitary causes of reproductive dysfunction. The drug is typically supplied as a sterile injectable solution and may be given as a single dose or as part of a stimulation test protocol, depending on the clinical application.
