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Alternate Names: Sesquient, Cerebyx, Pro-Epanutin
CAS No: 92134-98-0
PubChem CID: 56338
Mol Formula: C16H13N2Na2O6P
Mol Weight: 406.24 g/mol
IUPAC Name: disodium;(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methyl phosphate
Therapeutic use: Anti-epileptic drugs, Central Nervous System (CNS) Agents
Drug Class: Neurotransmitter agents
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Fosphenytoin Sodium is the sodium salt form of fosphenytoin, a prodrug that is hydrolyzed to the anticonvulsant phenytoin upon parental administration. Phenytoin exerts its effect most likely through an enhancement of sodium efflux from neurons in the motor cortex. This leads to a suppression of excessive neuronal firing and spread of seizure activity. Other physiologic effects from actions of phenytoin include modulation of the voltage-dependent calcium channels of neurons, inhibition of calcium flux across neuronal membranes and enhancement of sodium-potassium ATPase activity of neurons and glial cells.
