Find verified Duloxetine hydrochloride API manufacturers, suppliers, and distributors across the globe. Explore companies that offer high-purity Duloxetine hydrochloride for pharmaceutical use, along with product details, certifications, and reliable sourcing options. Compare prices, check availability, and connect directly with trusted suppliers for Duloxetine hydrochloride API.
Alternate Names: Duloxetine HCl, Dulane 20, Ariclaim
CAS No: 136434-34-9
PubChem CID: 60834
Mol Formula: C18H20ClNOS
Mol Weight: 333.9 g/mol
IUPAC Name: (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;hydrochloride
API Description: Duloxetine Hydrochloride is the hydrochloride salt of duloxetine, an orally bioavailable fluoxetine derivative belonging to the class of selective serotonin (5-HT) and norepinephrine (NE) reuptake inhibitors (SNRIs), with central pain inhibitory, anxiolytic and antidepressant activities. Upon oral administration, duloxetine selectively prevents the reuptake of 5-HT and NE via transporter complexes on the pre-synaptic membrane, thereby increasing the level of these neurotransmitters within the synaptic cleft. This potentiates serotonergic and noradrenergic activities in the central nervous system (CNS), and alleviates anxiety, depression, and neuropathy sensations, such as neuropathic pain.
