ethyl (2R,3R)-3-cyclopropyl-1-methylaziridine-2-carboxylate (CAS No: 2864383-32-2) is a key pharmaceutical intermediate used in the synthesis of APIs Zoldonrasib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: EX-A11808
CAS No: 2864383-32-2
PubChem CID: 166115921
Mol Formula: C9H15NO2
Mol Weight: 169.22 g/mol
Used in API: Zoldonrasib
IUPAC Name: ethyl (2R,3R)-3-cyclopropyl-1-methylaziridine-2-carboxylate
API Intermediate Description: Zoldonrasib (RMC-9805) is a selective KRAS G12D inhibitor, and ethyl (2R,3R)-3-cyclopropyl-1-methylaziridine-2-carboxylate is a chiral aziridine intermediate used in its synthesis. It contains a stereochemically defined aziridine ring, cyclopropyl group, and ethyl ester, providing a versatile building block for subsequent functionalization and coupling reactions. Further transformations of this intermediate contribute to the construction of advanced intermediates leading to the final zoldonrasib API.
